hrp0097p1-199 | Thyroid | ESPE2023

Investigating the Incidence of Mild Neonatal Hyperthyrotropinaemia, a Multicentre Study

Howard-James N , McGlacken-Byrne SM , Kernan R , Carolan EC , Murphy NP

Background: Mild isolated neonatal hyperthyrotropinaemia (HTT), defined as elevated thyroid stimulating hormone (TSH) with normal free thyroxine (FT4) concentrations, may be identified by newborn screening programmes for congenital hypothyroidism (CHT) or when neonatal thyroid function tests (TFTs) are performed for a clinical indication. Reported HTT incidence rates vary (from 0.001-0.1%)1. Case definition also varies, with some authors using a TSH...